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Changing Polygenic Penetrance on Phenotypes in the 20(th) Century Among Adults in the US Population
This study evaluates changes in genetic penetrance—defined as the association between an additive polygenic score and its associated phenotype—across birth cohorts. Situating our analysis within recent historical trends in the U.S., we show that, while height and BMI show increasing genotypic penetr...
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| Vydáno v: | Sci Rep |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4960614/ https://ncbi.nlm.nih.gov/pubmed/27456657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30348 |
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