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Changing Polygenic Penetrance on Phenotypes in the 20(th) Century Among Adults in the US Population
This study evaluates changes in genetic penetrance—defined as the association between an additive polygenic score and its associated phenotype—across birth cohorts. Situating our analysis within recent historical trends in the U.S., we show that, while height and BMI show increasing genotypic penetr...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4960614/ https://ncbi.nlm.nih.gov/pubmed/27456657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30348 |
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