New approaches in tail‐bleeding assay in mice: improving an important method for designing new anti‐thrombotic agents

This report describes a modified, simple, low‐cost and more sensitive method to determine bleeding patterns and haemoglobin concentration in a tail‐bleeding assay using BALB/c mice and tail tip amputation. The cut tail was immersed in Drabkin's reagent to promote erythrocyte lysis and haemoglob...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Exp Pathol
Hauptverfasser: Saito, Max Seidy, Lourenço, André Luiz, Kang, Hye Chung, Rodrigues, Carlos Rangel, Cabral, Lucio Mendes, Castro, Helena Carla, Satlher, Plínio Cunha
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
New Methods
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960579/
https://ncbi.nlm.nih.gov/pubmed/27377432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12182
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