The effects of genomic polymorphisms in one-carbon metabolism pathways on survival of gastric cancer patients received fluorouracil-based adjuvant therapy

5-fluorouracil (5-FU) is widely used to treat patients with gastric cancer (GC). However, the response rate is quite heterogeneous. The single nucleotide polymorphisms (SNPs) and their interactions of genes in the one-carbon metabolism (OCM) pathway, including Methylenetetrahydrofolate reductase (MT...

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Publicado no:Sci Rep
Main Authors: Zhao, Tingting, Xu, Zhi, Gu, Dongying, Wu, Peng, Huo, Xinying, Wei, Xiaowei, Tang, Yongfei, Gong, Weida, He, Ming-Liang, Chen, Jinfei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960563/
https://ncbi.nlm.nih.gov/pubmed/27456431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28019
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