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Identification and characterization of the role of c-terminal Src kinase in dengue virus replication

We screened a siRNA library targeting human tyrosine kinases in Huh-7 cells and identified c-terminal Src kinase (Csk) as one of the kinases involved in dengue virus replication. Knock-down of Csk expression by siRNAs or inhibition of Csk by an inhibitor reduced dengue virus RNA levels but did not a...

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Foilsithe in:Sci Rep
Main Authors: Kumar, Rinki, Agrawal, Tanvi, Khan, Naseem Ahmed, Nakayama, Yuji, Medigeshi, Guruprasad R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960526/
https://ncbi.nlm.nih.gov/pubmed/27457684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30490
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