Neuroprotective Properties of a Macrolide Antibiotic in a Mouse Model of Middle Cerebral Artery Occlusion: Characterization of the Immunomodulatory Effects and Validation of the Efficacy of Intravenous Administration

Repurposing the macrolide antibiotic azithromycin has recently been suggested as a promising neuroprotective strategy for the acute treatment of ischemic stroke. Here, we aim at further characterizing the immunomodulatory properties of intraperitoneal (i.p.) administration of this drug and, more imp...

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Bibliographic Details
Published in:Assay Drug Dev Technol
Main Authors: Amantea, Diana, Certo, Michelangelo, Petrelli, Francesco, Bagetta, Giacinto
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2016
Subjects:
Technical Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960494/
https://ncbi.nlm.nih.gov/pubmed/27392039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2016.728
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