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Clinical Development of the CDK4/6 Inhibitors Ribociclib and Abemaciclib in Breast Cancer

Clinical and preclinical data support a significant role for inhibitors of the cyclin-dependent kinases (CDKs) 4 and 6 in the treatment of patients with breast cancer. Recently, based on data showing improvement in progression-free survival, the use of palbociclib (Ibrance; Pfizer, Inc.) in combinat...

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Bibliografiske detaljer
Udgivet i:Breast Care (Basel)
Main Authors: Barroso-Sousa, Romualdo, Shapiro, Geoffrey I., Tolaney, Sara M.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger GmbH 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960359/
https://ncbi.nlm.nih.gov/pubmed/27493615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000447284
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