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Palbociclib: First CDK4/6 Inhibitor in Clinical Practice for the Treatment of Advanced HR-Positive Breast Cancer

Palbociclib is the first inhibitor of the cyclin-dependent kinases (CDK) 4 and 6 to be introduced into clinical practice. Preclinical investigations led to its clinical development in advanced hormone receptor (HR)-positive breast cancer. To date, 2 significant clinical trials have been fully publis...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Breast Care (Basel)
1. Verfasser: Ettl, Johannes
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger GmbH 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960350/
https://ncbi.nlm.nih.gov/pubmed/27493616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000447417
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