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Palbociclib: First CDK4/6 Inhibitor in Clinical Practice for the Treatment of Advanced HR-Positive Breast Cancer

Palbociclib is the first inhibitor of the cyclin-dependent kinases (CDK) 4 and 6 to be introduced into clinical practice. Preclinical investigations led to its clinical development in advanced hormone receptor (HR)-positive breast cancer. To date, 2 significant clinical trials have been fully publis...

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Detalhes bibliográficos
Publicado no:Breast Care (Basel)
Autor principal: Ettl, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger GmbH 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960350/
https://ncbi.nlm.nih.gov/pubmed/27493616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000447417
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