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Accurate spike estimation from noisy calcium signals for ultrafast three-dimensional imaging of large neuronal populations in vivo

Extracting neuronal spiking activity from large-scale two-photon recordings remains challenging, especially in mammals in vivo, where large noises often contaminate the signals. We propose a method, MLspike, which returns the most likely spike train underlying the measured calcium fluorescence. It r...

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Detalhes bibliográficos
Publicado no:Nat Commun
Principais autores: Deneux, Thomas, Kaszas, Attila, Szalay, Gergely, Katona, Gergely, Lakner, Tamás, Grinvald, Amiram, Rózsa, Balázs, Vanzetta, Ivo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960309/
https://ncbi.nlm.nih.gov/pubmed/27432255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12190
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