Neuronal Actin Dynamics, Spine Density and Neuronal Dendritic Complexity Are Regulated by CAP2

Actin remodeling is crucial for dendritic spine development, morphology and density. CAP2 is a regulator of actin dynamics through sequestering G-actin and severing F-actin. In a mouse model, ablation of CAP2 leads to cardiovascular defects and delayed wound healing. This report investigates the rol...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Kumar, Atul, Paeger, Lars, Kosmas, Kosmas, Kloppenburg, Peter, Noegel, Angelika A., Peche, Vivek S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960234/
https://ncbi.nlm.nih.gov/pubmed/27507934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00180
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