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Mitochondria, cholesterol and cancer cell metabolism

Given the role of mitochondria in oxygen consumption, metabolism and cell death regulation, alterations in mitochondrial function or dysregulation of cell death pathways contribute to the genesis and progression of cancer. Cancer cells exhibit an array of metabolic transformations induced by mutatio...

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Bibliographic Details
Published in:Clin Transl Med
Main Authors: Ribas, Vicent, García-Ruiz, Carmen, Fernández-Checa, José C.
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960093/
https://ncbi.nlm.nih.gov/pubmed/27455839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40169-016-0106-5
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