Adenomatous Polyposis Coli (APC) regulates miR17-92 cluster through β-catenin pathway in colorectal cancer

APC mutation is the most common genetic changes in sporadic colorectal cancer (CRC). Despite deregulations of miRNAs have been frequently reported in this malignancy, APC regulated miRNAs have not been extensively documented. Here, by employing an APC inducible cell line and array analysis, we ident...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Li, Yajuan, Lauriola, Mattia, Kim, Donghwa, Francesconi, Mirko, D'Uva, Gabriele, Shibata, Dave, Malafa, Mokenge P., Yeatman, Timothy J., Coppola, Domenico, Solmi, Rossella, Cheng, Jin Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960006/
https://ncbi.nlm.nih.gov/pubmed/26804172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.522
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