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Synthesis of Cyclic 1,3-Diols as Scaffolds for Spatially Directed Libraries

A useful design element in small molecule libraries is spatial diversity, in which binding moieties are systematically directed toward different regions of three-dimensional space. One way of achieving this is through the use of conformationally diverse scaffolds onto which various binding moieties...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Singh, Gurpreet, Aubé, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959890/
https://ncbi.nlm.nih.gov/pubmed/27087108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob00598e
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