Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-κB activation

Nuclear factor kappa B (NF-κB)-mediated transcription is an important mediator for cellular responses to DNA damage. Genotoxic agents trigger a 'nuclear-to-cytoplasmic' NF-κB activation signaling pathway; however, the early nuclear signaling cascade linking DNA damage and NF-κB activation...

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Vydáno v:eLife
Hlavní autoři: Fu, Kai, Sun, Xin, Wier, Eric M, Hodgson, Andrea, Liu, Yue, Sears, Cynthia L, Wan, Fengyi
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2016
Témata:
Cancer Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959885/
https://ncbi.nlm.nih.gov/pubmed/27458801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15018
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