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Activation of the Ca(2+)-sensing receptor increases renal claudin-14 expression and urinary Ca(2+) excretion

Kidney stones are a prevalent clinical condition imposing a large economic burden on the health-care system. Hypercalciuria remains the major risk factor for development of a Ca(2+)-containing stone. The kidney’s ability to alter Ca(2+) excretion in response to changes in serum Ca(2+) is in part med...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Physiol Renal Physiol
Hauptverfasser: Dimke, Henrik, Desai, Prajakta, Borovac, Jelena, Lau, Alyssa, Pan, Wanling, Alexander, R. Todd
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959880/
https://ncbi.nlm.nih.gov/pubmed/23283989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00263.2012
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