VNN1 promotes atherosclerosis progression in apoE(−/−) mice fed a high-fat/high-cholesterol diet

Accumulated evidence shows that vanin-1 (VNN1) plays a key part in glucose metabolism. We explored the effect of VNN1 on cholesterol metabolism, inflammation, apoptosis in vitro, and progression of atherosclerotic plaques in apoE(−/−) mice. Oxidized LDL (Ox-LDL) significantly induced VNN1 expression...

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Vydáno v:J Lipid Res
Hlavní autoři: Hu, Yan-Wei, Wu, Shao-Guo, Zhao, Jing-Jing, Ma, Xin, Lu, Jing-Bo, Xiu, Jian-cheng, Zhang, Yuan, Huang, Chuan, Qiu, Yu-Rong, Sha, Yan-Hua, Gao, Ji-Juan, Wang, Yan-Chao, Li, Shu-Fen, Zhao, Jia-Yi, Zheng, Lei, Wang, Qian
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959856/
https://ncbi.nlm.nih.gov/pubmed/27281478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M065565
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