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VNN1 promotes atherosclerosis progression in apoE(−/−) mice fed a high-fat/high-cholesterol diet
Accumulated evidence shows that vanin-1 (VNN1) plays a key part in glucose metabolism. We explored the effect of VNN1 on cholesterol metabolism, inflammation, apoptosis in vitro, and progression of atherosclerotic plaques in apoE(−/−) mice. Oxidized LDL (Ox-LDL) significantly induced VNN1 expression...
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| Udgivet i: | J Lipid Res |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Biochemistry and Molecular Biology
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4959856/ https://ncbi.nlm.nih.gov/pubmed/27281478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M065565 |
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