Does Anticoagulant Medication Alter Fracture-Healing? A Morphological and Biomechanical Evaluation of the Possible Effects of Rivaroxaban and Enoxaparin Using a Rat Closed Fracture Model

Low molecular weight heparin (LMWH) is routinely used to prevent thromboembolism in orthopaedic surgery, especially in the treatment of fractures or after joint-replacement. Impairment of fracture-healing due to increased bone-desorption, delayed remodelling and lower calcification caused by direct...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Prodinger, Peter Michael, Burgkart, Rainer, Kreutzer, Kilian, Liska, Franz, Pilge, Hakan, Schmitt, Andreas, Knödler, Martina, Holzapfel, Boris Michael, Hapfelmeier, Alexander, Tischer, Thomas, Bissinger, Oliver
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959754/
https://ncbi.nlm.nih.gov/pubmed/27455072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159669
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