Mapping Variation in Cellular and Transcriptional Response to 1,25-Dihydroxyvitamin D3 in Peripheral Blood Mononuclear Cells

The active hormonal form of vitamin D, 1,25-dihydroxyvitamin D (1,25D) is an important modulator of the immune system, inhibiting cellular proliferation and regulating transcription of immune response genes. In order to characterize the genetic basis of variation in the immunomodulatory effects of 1...

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Veröffentlicht in:PLoS One
Hauptverfasser: Kariuki, Silvia N., Maranville, Joseph C., Baxter, Shaneen S., Jeong, Choongwon, Nakagome, Shigeki, Hrusch, Cara L., Witonsky, David B., Sperling, Anne I., Di Rienzo, Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959717/
https://ncbi.nlm.nih.gov/pubmed/27454520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159779
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