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Type I Interferons in Newborns—Neurotoxicity versus Antiviral Defense

In most children and adults, primary infection with herpes simplex virus 1 (HSV-1) is asymptomatic. However, very rarely (incidence of 1 in 1,000,000), it can cause herpes simplex encephalitis (HSE). HSE also occurs in infants but with a much starker incidence of one in three. This age difference in...

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Bibliographic Details
Published in:mBio
Main Author: Bogunovic, Dusan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959667/
https://ncbi.nlm.nih.gov/pubmed/27190218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00639-16
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