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Denosumab could be a Potential Inhibitor of Valvular Interstitial Cells Calcification in vitro

OBJECTIVE: Denosumab is a fully human monoclonal antibody and novel antiresorptive agent that works by binding receptor activator of nuclear factor kappa-β ligand (RANKL) and inhibiting the signaling cascade that causes osteoclast maturation, activity, and survival. We aimed to elucidate the effect...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Cardiovasc Res
Hauptverfasser: Lerman, Daniel Alejandro, Prasad, Sai, Alotti, Nasri
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959558/
https://ncbi.nlm.nih.gov/pubmed/27468412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2324-8602.1000249
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