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The Inhibitory Site of a Diguanylate Cyclase Is a Necessary Element for Interaction and Signaling with an Effector Protein

Many bacteria contain large cyclic diguanylate (c-di-GMP) signaling networks made of diguanylate cyclases (DGCs) and phosphodiesterases that can direct cellular activities sensitive to c-di-GMP levels. While DGCs synthesize c-di-GMP, many DGCs also contain an autoinhibitory site (I-site) that binds...

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Detalles Bibliográficos
Publicado en:J Bacteriol
Main Authors: Dahlstrom, Kurt M., Giglio, Krista M., Sondermann, Holger, O'Toole, George A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959289/
https://ncbi.nlm.nih.gov/pubmed/27002135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00090-16
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