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Cardiolipins Act as a Selective Barrier to Toll-Like Receptor 4 Activation in the Intestine

Intestinal homeostasis mechanisms must protect the host intestinal tissue from endogenous lipopolysaccharides (LPSs) produced by the intestinal microbiota. In this report, we demonstrate that murine intestinal fecal lipids effectively block Toll-like receptor 4 (TLR4) responses to naturally occurrin...

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Bibliografiske detaljer
Udgivet i:Appl Environ Microbiol
Main Authors: Coats, Stephen R., Hashim, Ahmed, Paramonov, Nikolay A., To, Thao T., Curtis, Michael A., Darveau, Richard P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959216/
https://ncbi.nlm.nih.gov/pubmed/27208127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00463-16
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