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Increased MMP‐7 expression in biliary epithelium and serum underpins native liver fibrosis after successful portoenterostomy in biliary atresia

The molecular mechanisms underlying progressive liver fibrosis following surgical treatment of biliary atresia (BA) remain unclear. Our aim was to address hepatic gene and protein expression and serum levels of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) after successful por...

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Detalhes bibliográficos
Publicado no:J Pathol Clin Res
Main Authors: Kerola, Anna, Lampela, Hanna, Lohi, Jouko, Heikkilä, Päivi, Mutanen, Annika, Hagström, Jaana, Tervahartiala, Taina, Sorsa, Timo, Haglund, Caj, Jalanko, Hannu, Pakarinen, Mikko P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958739/
https://ncbi.nlm.nih.gov/pubmed/27499927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.50
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