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Association between itraconazole, a hedgehog-inhibitor, and bladder cancer
PURPOSE: Activation of Hedgehog (Hh) signaling has been implicated in early stages of bladder cancer development, while loss of Hh signaling has been described during progression to more invasive disease. Itraconazole, an antifungal, is the only azole known to be a potent Hh pathway antagonist. We e...
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| Publicado no: | J Urol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4958604/ https://ncbi.nlm.nih.gov/pubmed/26812305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2016.01.089 |
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