Genetic variants in the mTOR pathway and interaction with body size and weight gain on breast cancer risk in African-American and European-American women

PURPOSE: Positive energy imbalance and growth factors linked to obesity promote the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin (mTOR) pathway. As the obesity-breast cancer associations differ between European-American (EA) and African-American (AA) women, we investigated genetic...

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Bibliographic Details
Published in:Cancer Causes Control
Main Authors: Cheng, Ting-Yuan David, Shankar, Jyoti, Zirpoli, Gary, Roberts, Michelle R., Hong, Chi-Chen, Bandera, Elisa V., Ambrosone, Christine B., Yao, Song
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958603/
https://ncbi.nlm.nih.gov/pubmed/27314662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-016-0774-x
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