The HPV16 E7 Oncoprotein Disrupts Dendritic Cell Function and Induces the Systemic Expansion of CD11b(+)Gr1(+) Cells in a Transgenic Mouse Model

Objective. The aim of this study was to analyze the effects of the HPV16 E7 oncoprotein on dendritic cells (DCs) and CD11b(+)Gr1(+) cells using the K14E7 transgenic mouse model. Materials and Methods. The morphology of DCs was analyzed in male mouse skin on epidermal sheets using immunofluorescence...

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Veröffentlicht in:Biomed Res Int
Hauptverfasser: Damian-Morales, Gabriela, Serafín-Higuera, Nicolás, Moreno-Eutimio, Mario Adán, Cortés-Malagón, Enoc M., Bonilla-Delgado, José, Rodríguez-Uribe, Genaro, Ocadiz-Delgado, Rodolfo, Lambert, Paul F., Gariglio, Patricio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958469/
https://ncbi.nlm.nih.gov/pubmed/27478837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8091353
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