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Notch maintains Drosophila type II neuroblasts by suppressing expression of the Fez transcription factor Earmuff
Notch signaling is crucial for maintaining neural stem cell (NSC) self-renewal and heterogeneity; however, the underlying mechanism is not well understood. In Drosophila, loss of Notch prematurely terminates the self-renewal of larval type II neuroblasts (NBs, the Drosophila NSCs) and transforms typ...
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| Publicado no: | Development |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4958340/ https://ncbi.nlm.nih.gov/pubmed/27151950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.136184 |
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