Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing

New hair follicles (HFs) do not form in adult mammalian skin unless epidermal Wnt signalling is activated genetically or within large wounds. To understand the postnatal loss of hair forming ability we monitored HF formation at small circular (2 mm) wound sites. At P2, new HFs formed in back skin, b...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Development
Prif Awduron: Rognoni, Emanuel, Gomez, Celine, Pisco, Angela Oliveira, Rawlins, Emma L., Simons, Ben D., Watt, Fiona M., Driskell, Ryan R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2016
Pynciau:
Stem Cells and Regeneration
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958333/
https://ncbi.nlm.nih.gov/pubmed/27287810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.131797
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