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Long-term drug administration in the adult zebrafish using oral gavage for cancer preclinical studies

Zebrafish are a major model for chemical genetics, and most studies use embryos when investigating small molecules that cause interesting phenotypes or that can rescue disease models. Limited studies have dosed adults with small molecules by means of water-borne exposure or injection techniques. Cha...

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Bibliographic Details
Published in:Dis Model Mech
Main Authors: Dang, Michelle, Henderson, Rachel E., Garraway, Levi A., Zon, Leonard I.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958307/
https://ncbi.nlm.nih.gov/pubmed/27482819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.024166
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