Peroxisome proliferator-activated receptor alpha acts as a mediator of endoplasmic reticulum stress-induced hepatocyte apoptosis in acute liver failure

Peroxisome proliferator-activated receptor α (PPARα) is a key regulator to ameliorate liver injury in cases of acute liver failure (ALF). However, its regulatory mechanisms remain largely undetermined. Endoplasmic reticulum stress (ER stress) plays an important role in a number of liver diseases. Th...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Dis Model Mech
Autori principali: Zhang, Li, Ren, Feng, Zhang, Xiangying, Wang, Xinxin, Shi, Hongbo, Zhou, Li, Zheng, Sujun, Chen, Yu, Chen, Dexi, Li, Liying, Zhao, Caiyan, Duan, Zhongping
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958306/
https://ncbi.nlm.nih.gov/pubmed/27482818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.023242
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