JC Polyomavirus Infection of Primary Human Renal Epithelial Cells Is Controlled by a Type I IFN-Induced Response

The JC and BK human polyomaviruses (JCPyV and BKPyV, respectively) establish lifelong persistent infections in the kidney. In immunosuppressed individuals, JCPyV causes progressive multifocal leukoencephalopathy (PML), a fatal neurodegenerative disease, and BKPyV causes polyomavirus-associated nephr...

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發表在:mBio
Main Authors: Assetta, Benedetta, De Cecco, Marco, O’Hara, Bethany, Atwood, Walter J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2016
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958256/
https://ncbi.nlm.nih.gov/pubmed/27381292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00903-16
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