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Glutathione-Disrupted Biofilms of Clinical Pseudomonas aeruginosa Strains Exhibit an Enhanced Antibiotic Effect and a Novel Biofilm Transcriptome

Pseudomonas aeruginosa infections result in high morbidity and mortality rates for individuals with cystic fibrosis (CF), with premature death often occurring. These infections are complicated by the formation of biofilms in the sputum. Antibiotic therapy is stymied by antibiotic resistance of the b...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Klare, William, Das, Theerthankar, Ibugo, Amaye, Buckle, Edwina, Manefield, Mike, Manos, Jim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958218/
https://ncbi.nlm.nih.gov/pubmed/27161630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02919-15
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