Validation and Application of a Dried Blood Spot Assay for Biofilm-Active Antibiotics Commonly Used for Treatment of Prosthetic Implant Infections

Dried blood spot (DBS) antibiotic assays can facilitate pharmacokinetic (PK)/pharmacodynamic (PD) studies in situations where venous blood sampling is logistically difficult. We sought to develop, validate, and apply a DBS assay for rifampin (RIF), fusidic acid (FUS), and ciprofloxacin (CIP). These...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Knippenberg, Ben, Page-Sharp, Madhu, Salman, Sam, Clark, Ben, Dyer, John, Batty, Kevin T., Davis, Timothy M. E., Manning, Laurens
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958200/
https://ncbi.nlm.nih.gov/pubmed/27270283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00756-16
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