IKKβ-mediated inflammatory myeloid cell activation exacerbates experimental autoimmune encephalomyelitis by potentiating Th1/Th17 cell activation and compromising blood brain barrier

BACKGROUND: The inflammatory myeloid cell activation is one of the hallmarks of experimental autoimmune encephalomyelitis (EAE), yet the in vivo role of the inflammatory myeloid cell activation in EAE has not been clearly resolved. It is well-known that IKK/NF-κB is a key signaling pathway that regu...

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Publicado no:Mol Neurodegener
Main Authors: Lee, Min Jung, Bing, So Jin, Choi, Jonghee, Jang, Minhee, Lee, Gihyun, Lee, Hyunkyoung, Chang, Byung Soo, Jee, Youngheun, Lee, Sung Joong, Cho, Ik-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957872/
https://ncbi.nlm.nih.gov/pubmed/27450563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0116-1
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