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The immobilization of a direct thrombin inhibitor to a polyurethane as a nonthrombogenic surface coating for extracorporeal circulation

A biomaterial with both antithrombin and antiplatelet properties is the ideal surface for use in extracorporeal circulation (ECC) as it targets both fibrin generation and platelet adhesion. A hemocompatible surface coating avoids the need for systemic anticoagulation by providing a local anticoagula...

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Dades bibliogràfiques
Publicat a:J Mater Chem B Mater Biol Med
Autors principals: Yu, Jane, Brisbois, Elizabeth, Handa, Hitesh, Annich, Gail, Meyerhoff, Mark, Bartlett, Robert, Major, Terry
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957704/
https://ncbi.nlm.nih.gov/pubmed/27458521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C5TB02419F
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