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Deficiency of plasminogen activator inhibitor 2 in plasma of patients with hereditary angioedema with normal C1 inhibitor levels

BACKGROUND: Hereditary angioedema with normal C1 inhibitor levels (HAE-N) is associated with a Factor XII mutation in 30% of subjects; however, the role of this mutation in the pathogenesis of angioedema is unclear. OBJECTIVE: We sought evidence of abnormalities in the pathways of bradykinin formati...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Joseph, Kusumam, Tholanikunnel, Baby G., Wolf, Bethany, Bork, Konrad, Kaplan, Allen P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957703/
https://ncbi.nlm.nih.gov/pubmed/26395818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.07.041
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