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PIM kinase (and Akt) biology and signaling in tumors
The initiation and progression of human cancer is frequently linked to the uncontrolled activation of survival kinases. Two such pro-survival kinases that are commonly amplified in cancer are PIM and Akt. These oncogenic proteins are serine/threonine kinases that regulate tumorigenesis by phosphoryl...
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| Publicado no: | Pharmacol Ther |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4957637/ https://ncbi.nlm.nih.gov/pubmed/25749412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2015.03.001 |
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