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Extinction of conditioned opiate withdrawal in rats in a two-chambered place conditioning apparatus

Conditioned opiate withdrawal contributes to relapse in addicts and can be studied in rats using the opiate withdrawal-induced conditioned place aversion (OW-CPA) paradigm. Attenuation of conditioned withdrawal through extinction may be beneficial in the treatment of addiction. Here we describe a pr...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Protoc
Hauptverfasser: Myers, Karyn M., Bechtholt-Gompf, Anita J., Coleman, Brian R., Carlezon, William A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957553/
https://ncbi.nlm.nih.gov/pubmed/22362157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2011.458
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