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Boosting the discriminatory power of sparse survival models via optimization of the concordance index and stability selection

BACKGROUND: When constructing new biomarker or gene signature scores for time-to-event outcomes, the underlying aims are to develop a discrimination model that helps to predict whether patients have a poor or good prognosis and to identify the most influential variables for this task. In practice, t...

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Detalles Bibliográficos
Publicado en:BMC Bioinformatics
Main Authors: Mayr, Andreas, Hofner, Benjamin, Schmid, Matthias
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957316/
https://ncbi.nlm.nih.gov/pubmed/27444890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1149-8
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