TSG-6 secreted by human umbilical cord-MSCs attenuates severe burn-induced excessive inflammation via inhibiting activations of P38 and JNK signaling

The hMSCs have become a promising approach for inflammation treatment in acute phase. Our previous study has demonstrated that human umbilical cord-MSCs could alleviate the inflammatory reaction of severely burned wound. In this study, we further investigated the potential role and mechanism of the...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Liu, Lingying, Song, Huifeng, Duan, Hongjie, Chai, Jiake, Yang, Jing, Li, Xiao, Yu, Yonghui, Zhang, Xulong, Hu, Xiaohong, Xiao, Mengjing, Feng, Rui, Yin, Huinan, Hu, Quan, Yang, Longlong, Du, Jundong, Li, Tianran
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957124/
https://ncbi.nlm.nih.gov/pubmed/27444207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30121
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