Features of an altered AMPK metabolic pathway in Gilbert’s Syndrome, and its role in metabolic health

Energy metabolism, involving the ATP-dependent AMPK-PgC-Ppar pathway impacts metabolic health immensely, in that its impairment can lead to obesity, giving rise to disease. Based on observations that individuals with Gilbert’s syndrome (GS; UGT1A1(*)28 promoter mutation) are generally lighter, leane...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Mölzer, Christine, Wallner, Marlies, Kern, Carina, Tosevska, Anela, Schwarz, Ursula, Zadnikar, Rene, Doberer, Daniel, Marculescu, Rodrig, Wagner, Karl-Heinz
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956769/
https://ncbi.nlm.nih.gov/pubmed/27444220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30051
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