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Delayed CTLA4-Ig treatment reverses ongoing alloantibody responses and rescues allografts from acute rejection
Antibody-mediated rejection has emerged as the leading cause of late graft loss in kidney transplant recipients, and inhibition of donor-specific antibody production should lead to improved transplant outcomes. The fusion protein CTLA4-Ig blocks T-cell activation and consequently inhibits T-dependen...
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| Опубликовано в: : | Am J Transplant |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4956497/ https://ncbi.nlm.nih.gov/pubmed/26928966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13761 |
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