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Metallothionein-1G Facilitates Sorafenib Resistance through Inhibition of Ferroptosis

Hepatocellular carcinoma (HCC) is a major cause of cancer-related death worldwide and currently has the fastest rising incidence of all cancers. Sorafenib was originally identified as an inhibitor of multiple oncogenic kinases and remains the only approved systemic therapy for advanced HCC. However,...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Sun, Xiaofang, Niu, Xiaohua, Chen, Ruochan, He, Wenyin, Chen, De, Kang, Rui, Tang, Daolin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956496/
https://ncbi.nlm.nih.gov/pubmed/27015352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28574
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