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Protein engineering by highly parallel screening of computationally designed variants

Current combinatorial selection strategies for protein engineering have been successful at generating binders against a range of targets; however, the combinatorial nature of the libraries and their vast undersampling of sequence space inherently limit these methods due to the difficulty in finely c...

詳細記述

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書誌詳細
出版年:Sci Adv
主要な著者: Sun, Mark G. F., Seo, Moon-Hyeong, Nim, Satra, Corbi-Verge, Carles, Kim, Philip M.
フォーマット: Artigo
言語:Inglês
出版事項: American Association for the Advancement of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956399/
https://ncbi.nlm.nih.gov/pubmed/27453948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600692
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