Rheumatoid Arthritis Disease Activity Is Determinant for ABCB1 and ABCG2 Drug-Efflux Transporters Function

OBJECTIVE: To compare drug efflux function of ABCB1 and ABCG2 transporters in rheumatoid arthritis (RA) patients with active disease and in remission. METHODS: Twenty two active RA patients (DAS28 ≥3.2) and 22 patients in remission (DAS28<2.6) were selected from an early RA clinic. All patients w...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Atisha-Fregoso, Yemil, Lima, Guadalupe, Pascual-Ramos, Virginia, Baños-Peláez, Miguel, Fragoso-Loyo, Hilda, Jakez-Ocampo, Juan, Contreras-Yáñez, Irazú, Llorente, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956301/
https://ncbi.nlm.nih.gov/pubmed/27442114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159556
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