An Optimized Method for Accurate Fetal Sex Prediction and Sex Chromosome Aneuploidy Detection in Non-Invasive Prenatal Testing

Massively parallel sequencing (MPS) combined with bioinformatic analysis has been widely applied to detect fetal chromosomal aneuploidies such as trisomy 21, 18, 13 and sex chromosome aneuploidies (SCAs) by sequencing cell-free fetal DNA (cffDNA) from maternal plasma, so-called non-invasive prenatal...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Ting, He, Quanze, Li, Haibo, Ding, Jie, Wen, Ping, Zhang, Qin, Xiang, Jingjing, Li, Qiong, Xuan, Liming, Kong, Lingyin, Mao, Yan, Zhu, Yijun, Shen, Jingjing, Liang, Bo, Li, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956272/
https://ncbi.nlm.nih.gov/pubmed/27441628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159648
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