Anisotropic stress orients remodelling of mammalian limb bud ectoderm

The physical forces that drive morphogenesis are not well characterized in vivo, especially among vertebrates. In the early limb bud, dorsal and ventral ectoderm converge to form the apical ectodermal ridge (AER), although the underlying mechanisms are unclear. By live imaging mouse embryos, we show...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Lau, Kimberly, Tao, Hirotaka, Liu, Haijiao, Wen, Jun, Sturgeon, Kendra, Sorfazlian, Natalie, Lazic, Savo, Burrows, Jeffrey T. A., Wong, Michael D., Li, Danyi, Deimling, Steven, Ciruna, Brian, Scott, Ian, Simmons, Craig, Henkelman, R. Mark, Williams, Trevor, Hadjantonakis, Anna-Katerina, Fernandez-Gonzalez, Rodrigo, Sun, Yu, Hopyan, Sevan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955842/
https://ncbi.nlm.nih.gov/pubmed/25893915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3156
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