Llwytho...

Loss of protein association causes cardiolipin degradation in Barth syndrome

Cardiolipin is a specific mitochondrial phospholipid that has a high affinity for proteins and that stabilizes the assembly of supercomplexes involved in oxidative phosphorylation. We found that sequestration of cardiolipin in protein complexes is critical to protect it from degradation. The turnove...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Chem Biol
Prif Awduron: Xu, Yang, Phoon, Colin K.L., Berno, Bob, D’Souza, Kenneth, Hoedt, Esthelle, Zhang, Guoan, Neubert, Thomas A., Epand, Richard M., Ren, Mindong, Schlame, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955704/
https://ncbi.nlm.nih.gov/pubmed/27348092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2113
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