IFI44L promoter methylation as a blood biomarker for systemic lupus erythematosus

OBJECTIVE: Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease with limited reliable diagnostic biomarkers. We investigated whether gene methylation could meet sensitivity and specificity criteria for a robust biomarker. METHODS: IFI44L promoter methylation was examined using DN...

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Vydáno v:Ann Rheum Dis
Hlavní autoři: Zhao, Ming, Zhou, Yin, Zhu, Bochen, Wan, Mengjie, Jiang, Tingting, Tan, Qiqun, Liu, Yan, Jiang, Juqing, Luo, Shuaihantian, Tan, Yixin, Wu, Haijing, Renauer, Paul, Gutiérrez, Maria del Mar Ayala, Palma, Maria Jesús Castillo, Castro, Rafaela Ortega, Fernández-Roldán, Concepción, Raya, Enrique, Faria, Raquel, Carvalho, Claudia, Alarcón-Riquelme, Marta E, Xiang, Zhongyuan, Chen, Jinwei, Li, Fen, Ling, Guanghui, Zhao, Hongjun, Liao, Xiangping, Lin, Youkun, Sawalha, Amr H, Lu, Qianjin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955646/
https://ncbi.nlm.nih.gov/pubmed/26787370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2015-208410
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