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Post-translational Claisen Condensation and Decarboxylation en Route to the Bicyclic Core of Pantocin A

Pantocin A (PA) is a member of the growing family of ribosomally encoded and post-translationally modified peptide natural products (RiPPs). PA is much smaller than most known RiPPs, a tripeptide with a tight bicyclic core that appears to be cleaved from the middle of a larger 30-residue precursor p...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Ghodge, Swapnil V., Biernat, Kristen A., Bassett, Sarah Jane, Redinbo, Matthew R., Bowers, Albert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955399/
https://ncbi.nlm.nih.gov/pubmed/27088303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b13529
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