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CXCL12 expression promotes esophageal squamous cell carcinoma proliferation and worsens the prognosis

BACKGROUND: The chemokine CXCL12 and its corresponding receptor CXCR4 are key players in the development of several cancers. Therefore, we hypothesized that there is a functional causality between CXCL12 expression and tumor progression in patients with esophageal squamous cell carcinoma (ESCC). MET...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Cancer
Hauptverfasser: Uchi, Yusuke, Takeuchi, Hiroya, Matsuda, Sachiko, Saikawa, Yoshiro, Kawakubo, Hirofumi, Wada, Norihito, Takahashi, Tsunehiro, Nakamura, Rieko, Fukuda, Kazumasa, Omori, Tai, Kitagawa, Yuko
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955220/
https://ncbi.nlm.nih.gov/pubmed/27439769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2555-z
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